Opportunities

Positions

We are actively looking for highly motivated postdoctoral fellows, graduate and undergraduate students. We broadly study lymphatic and vascular biology, cancer biology, immunoengineering, and regenerative medicine by employing 3D organs-on-chip in vitro platforms, molecular biology methods, and in vivo animal models. We encourage open-minded persons from different backgrounds (biology, bioengineering, mechanical engineering, chemistry, medicine, and relevant fields) to apply for the positions.

1. Engineer positions (Postdoctoral, Graduate, Undergraduate):
[Microfluidics]
– Designing, fabrication (soft lithography), and characterization of microfluidic devices, lab-on-chip, organ-on-chip, 3D cellularity, tissue level in vitro modeling
– Cell seeding, cell culturing & maintaining on-chip; and investigating cell mechanics, cell-cell interactions, cell secretome, cell morphology on-chip
– Experience in developing tissue-level 3D mono/multi-cellular strucutre in vitro is a plus.
– Experience in organoids, stem cells, multicellular behaviors, cells in shear stress is a plus.
– Postdoctoral applicants must have a PhD degree in biomedical engineering, bioengineering, mechanical engineering or related field and have at least one first-authored publication in premier journals. The representative papers must focus on bio-oriented topics, rather than a device fabrication itself or other applications.

2. Scientist positions (Postdoctoral, Graduate, Undergraduate):
[Immunology]
– We look for Immunology Reseachers who can deepen our understanding of adaptive immunity and lymph node/lymphoid organ biology.
– Purification, adaptation, activation, and FACS characterization of immune cells (dendritic cells, T/B lymphocytes) obtained from animal and human samples.
– Monitoring immunity in vitro and in vivo.
– Modeling systemic/local infections in animal models and in vitro models.
– In vivo imaging (live or fixed samples) of immune cells and lymphoid organs in mice.
– Postdoctoral applicants must have a PhD degree in biomedical sciences (immunology, microbiology, infections, lymph nodes, etc) or related field and have at least one first-authored publication in premier journals.
– Expertise in lymph nodes, lymphoid organs is a plus.

[Vascular Biology]
– We look for Vascular Biology Reseachers who can deepen the understanding of blood and lymphatic vascular morphogenesis, homeostasis, and pathgenesis.
– Purification, maintaining and culturing human blood/lymphatic vascular endothelial cells and vascular mural cells (pericytes, smooth muscle cells, etc) using animal and human samples.
– Monitoring vascular morphology and function in vitro and in vivo.
– Monitoring tumor/immune cell interactions to vasculatures in vitro and in vivo.
– Expertise in in vivo implantation of engineered tissues is a plus.
– Expertise in vascular disease animal models in vivo (lymphedema, hypertension, vascular leakage, etc) is a plus.
– Postdoctoral applicants must have a PhD degree in biomedical sciences (vascular biology, lymphatic biology, etc) or related field and have at least one first-authored publication in premier journals.

[Cancer Biology]
– We look for Cancer Biology Reseachers who can deepen our understanding of tumor initiation, progression, interactions to blood and lymphatic vascular structures.
– Knowledge in mechanobiolgy of epithelial tumor cells is a plus
– Monitoring tumor interactions to vasculature in vitro and in vivo.
– Tumor immunotherapy, tumor metabolism, tumor metastasis, resistance.
– Postdoctoral applicants must have a PhD degree in biomedical sciences (cancer biology) or related field and have at least one first-authored publication in premier journals.

How to apply:
Send your coverletter and current CV that includes your degree information, publications, and the list of 3 references to the email: el767@cornell.edu

Collaborations

 “Organ-specific lymphatics and their functions”

Lymphatics exist throughout the body. Lymphatics play crucial roles in diverse organs, such as the heart (cholesterol homeostasis), eyes (Schlemm’s canal), lungs (fluid removal at birth), GI tract (fat/lipid absorption via lacteals), and brain (removing wastes, modulating neuro-immunity). We developed an “on-chip” model for 3D lymphatic vessels and lymphatic drainage or lymphatic interactions to other cell types. We are interested in collaborations with other researchers working on “organ-specific lymphatics and their functions”. We would like to provide platforms of in vitro 3D devices of lymphatics that do not require specialist expertise but may facilitate deeper mechanistic studies. We hope that the model systems could be easily adapted by other laboratories and impact their scientific discoveries to broadly contribute to the lymphatic research community.

Please contact Dr. Lee (e-mail: el767@cornell.edu) for more information.

 

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